PNL8 COST-EFFECTIVENESS OF BETAHISTINE VS CINNARIZINE FOR VERTIGO

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Betahistine or Cinnarizine for treatment of Meniere's disease.

INTRODUCTION Meniere's disease is a condition with sudden attacks of vertigo with nausea and vomiting accompanied by loss of hearing and buzzing sensation in the ears, most commonly unilateral. The exact cause of the disease is unknown. Betahistine is the analogue of histamine with weaker agonistic effect on histamine H1 receptors and stronger effect on histamine H3 receptors, while Cinnarizine...

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Association of cinnarizine and betahistine in prophylactic therapy for Ménière's disease with and without migraine

Prophylactic therapy of Ménière's disease (MD) includes betahistine and calcium-blockers (the latter also useful for migraine prevention). The aim of our work was to assess the efficacy of combined therapy with cinnarizine and betahistine in MD subjects both with and without migraine and poorly responsive to betahistine alone. Fifty-two MD subjects were included who were poorly responsive to be...

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Cost-effectiveness of the diagnostic evaluation of vertigo.

OBJECTIVE To evaluate the cost-effectiveness of several diagnostic tests used in the evaluation of vertigo. STUDY DESIGN Cost-effectiveness analysis, using data from retrospective case review. METHODS Charts and test results were reviewed from 192 outpatients seen in an academic tertiary referral center for evaluation of vertigo. Cost-effectiveness analysis was performed using decision anal...

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Effectiveness of betahistine (48 mg/day) in patients with vestibular vertigo during routine practice: The VIRTUOSO study

BACKGROUND Vestibular vertigo is associated with substantially reduced quality of life. Betahistine is effective in improving vertigo-associated symptoms, with longer treatment periods leading to greater improvements; however, it is not known whether these effects persist after treatment cessation. METHODS VIRTUOSO was a prospective, multinational, non-comparative, post-marketing observationa...

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Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study

OBJECTIVE To assess the efficacy and safety of cinnarizine for the prophylaxis of migraine associated vertigo in the vestibular migraine and migraine with brainstem aura. BACKGROUND Vestibular migraine and migraine with brainstem aura are two principal clinical syndromes that frequently are associated with vertigo. Since cinnarizine is a well-tolerated calcium channel blocker which has accept...

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ژورنال

عنوان ژورنال: Value in Health

سال: 2005

ISSN: 1098-3015

DOI: 10.1016/s1098-3015(10)67547-x